Eric Dane played Dr. Mark Sloan, aka “McSteamy,” on “Grey’s Anatomy” for six seasons, but he’s not done wooing his audiences yet. In 2025, Dane returned to TV on another medical drama, making his “Brilliant Minds” debut as “Bronx-Gen’s favorite silver fox.”
Dane revealed in April that he’d been diagnosed with amyotrophic lateral sclerosis, known as ALS. See the actor’s career in the spotlight from the early 2000’s to now, including here as he attends the “Countdown” premiere and afterparty on June 18, 2025, in Los Angeles.Frazer Harrison, Getty Images For Prime Video
Rebecca Gayheart and Eric Dane attend the Chrysalis Third Annual Butterfly Ball at a private residence on April 17, 2004, in Beverly Hills, California. The former couple, who share two children, got married that year.
Eric Dane during a 2004 celebrity surfing competition in Malibu, California.
From left: Publisher of OK! Magazine Tom Morrissey, general manager of A&E Robert DeBitetto, actor John Stamos, executive producer Craig Zadan, actor Eric Dane and entertainment media director of GLAAS Damon Romine arrive at the premiere of A&E original film “Wedding Wars” at the ArcLight Theater on Dec. 4, 2006, in Los Angeles.
Eric Dane and Patrick Dempsey pose during the 33rd annual People’s Choice Awards held at the Shrine Auditorium on Jan. 9, 2007, in Los Angeles.
Sara Ramirez and Eric Dane arrive at the 33rd annual People’s Choice Awards held at the Shrine Auditorium on Jan. 9, 2007, in Los Angeles.
From left, top to bottom: Ellen Pompeo, Kate Walsh, Chandra Wilson, Sandra Oh, Katherine Heigl, Sara Ramirez, Justin Chambers, Patrick Dempsey, James Pickens Jr., Eric Dane and T.R. Knight, winners of the ensemble in a drama series award for “Grey’s Anatomy” pose in the press room during the 13th annual Screen Actors Guild Awards held at the Shrine Auditorium on Jan. 28, 2007, in Los Angeles.
Eric Dane, left, and Patrick Dempsey, winners of the ensemble in a drama series award for “Grey’s Anatomy” pose in the press room during the 13th annual Screen Actors Guild Awards held at the Shrine Auditorium on Jan. 28, 2007, in Los Angeles.
Eric Dane and Ellen Pompeo attend a party for Dane and “Grey’s Anatomy” cast members hosted by Men’s Heath magazine at Tenjune May 14, 2007, in New York City.
Eric Dane arrives at the 12th annual GQ magazine Men of the Year celebration, Dec. 5, 2007, in Hollywood, California.
Eric Dane starred alongside Jennifer Aniston, right, and Owen Wilson, center, in “Marley & Me.” They arrived together at the premiere at the Mann Village Theater on Dec. 11, 2008, in Westwood, California.
Eric Dane and Rebecca Gayheart arrive at the premiere of New Line Cinema’s “Valentine’s Day” on Feb. 8, 2010, in Hollywood, California.
Members of the “Burlesque” cast — Eric Dane, Stanley Tucci, Christina Aguilera, Cher, Cam Gigandet and Julianne Hough — pose at the Four Seasons Hotel on Nov. 14, 2010, in Los Angeles.
Eric Dane arrives at the exclusive Filmmakers Dinner during the Cannes International Film Festival on May 21, 2012, in Cap d’Antibes, France.
Lena Gercke and Eric Dane attend a party to celebrate the fifth anniversary of TV channel TNT Serie at Kesselhalle on May 8, 2014, in Munich, Germany.
The Secretary of the Navy Ray Mabus, center, and Admiral Dawn Cutler present actor Eric Dane with a shadow box containing Navy medals earned by his father at the TNT “The Last Ship” Washington D.C. screening at The Newseum on June 12, 2015, in Washington, D.C.
Eric Dane speaks on stage at “The Last Ship” panel at Comic-Con on July 9, 2015, in San Diego, California.
Rebecca Gayheart, right, and Eric Dane with their children, Georgia Dane and Billie Beatrice Dane, at the 16th annual Chrysalis Butterfly Ball on June 3, 2017, in Los Angeles.
Adam Baldwin, Bridget Regan and Eric Dane at TNT’s “The Last Ship” panel and exclusive sneak peek for Season 4 during Comic-Con on July 23, 2017, in San Diego, California.
Patrick Mahomes, Eric Dane, Lilly Singh and Jared Goff attend the 2019 ESPYs at Microsoft Theater on July 10, 2019, in Los Angeles.
From left: Alexa Demie, Hunter Schafer, Eric Dane, Maude Apatow, Zendaya, Barbie Ferreira, Sydney Sweeney, Sam Levinson and Colman Domingo attend the HBO Max FYC event for “Euphoria” at Academy Museum of Motion Pictures on April 20, 2022, in Los Angeles.
John C. McGinley and Eric Dane, right, who was the 2022 Quincy Jones Exceptional Advocacy Award Recipient, attend the Global Down Syndrome Foundation’s 14th annual Be Beautiful Be Yourself fashion show at the Sheraton Downtown Denver Hotel on Nov. 12, 2022, in Denver.
Eric Dane and his daughters Billie Beatrice Dane and Georgia Dane attend the premiere of “Bad Boys: Ride or Die” at the TCL Chinese Theatre in Hollywood, California, on May 30, 2024.
Eric Dane and filmmaker Janell Shirtcliff attend Prime Video’s “Countdown” premiere at the Harmony Gold theatre in Los Angeles on June 18, 2025.
Eric Dane shakes hands with Medicare and Medicaid Administrator Mehmet Oz during a news conference to discuss health insurance at the Department of Health and Human Services Headquarters in Washington, D.C., on June 23, 2025. During the press conference Kennedy and Oz announced a plan they hope will streamline pre-authorizations for health procedures by health insurance providers.